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Showing posts with label Lymph Nodes. Show all posts
Showing posts with label Lymph Nodes. Show all posts

Tuesday, October 3, 2017

“Male Breast Cancer Awareness”




Male breast cancer is a rare cancer that forms in the breast tissue of men. Though breast cancer is most commonly thought of as a woman's disease, male breast cancer does occur.

Male breast cancer is most common in older men, though it can occur at any age.

Men diagnosed with male breast cancer at an early stage have a good chance for a cure. Still, many men delay seeing their doctors if they notice one of the usual signs or symptoms, such as a breast lump. For this reason, many male breast cancers are diagnosed when the disease is more advanced.

Signs and symptoms of male breast cancer can include:
  • A painless lump or thickening in your breast tissue;
  • Changes to the skin covering your breast, such as dimpling, puckering, redness or scaling;
  • Changes to your nipple, such as redness or scaling, or a nipple that begins to turn inward;
  • Discharge from your nipple.

When to see a doctor?

Make an appointment with your doctor if you have any persistent signs or symptoms that worry you.

It's not clear what causes male breast cancer.

Doctors know that male breast cancer occurs when some breast cells divide more rapidly than healthy cells do. The accumulating cells form a tumor that may spread (metastasize) to nearby tissue, to the lymph nodes or to other parts of the body.

Where breast cancer begins in men?

Everyone is born with a small amount of breast tissue. Breast tissue consists of milk-producing glands (lobules), ducts that carry milk to the nipples, and fat.
During puberty, women begin developing more breast tissue, and men do not. But because men are born with a small amount of breast tissue, they can develop breast cancer.

Types of breast cancer diagnosed in men include:
  • Cancer that begins in the milk ducts (ductal carcinoma). Nearly all male breast cancer is ductal carcinoma;
  • Cancer that begins in the milk-producing glands (lobular carcinoma). This type is rare in men because they have few lobules in their breast tissue;
  • Cancer that spreads to the nipple (Paget's disease of the nipple). Rarely, male breast cancer forms in the milk ducts and spreads to the nipple, causing crusty, scaly skin around the nipple.

Inherited genes that increase breast cancer risk

Some men inherit abnormal (mutated) genes from their parents that increase the risk of breast cancer. Mutations in one of several genes, especially a gene called BRCA2, put you at greater risk of developing breast and prostate cancers.

These genes normally make proteins that keep cells from growing abnormally — which helps prevent cancer. But mutated genes aren't as effective at protecting you from cancer.

Meeting with a genetic counselor and undergoing genetic testing can determine whether you carry gene mutations that increase your risk of breast cancer — and if you can pass this gene along to your children, both boys and girls. Discuss the benefits and risks of genetic testing with your doctor.

Factors that increase the risk of male breast cancer include:
  • Older age. Your risk of male breast cancer increases as you age. The peak incidence of male breast cancer occurs between the ages of 68 and 71.
  • Exposure to estrogen. If you take estrogen-related drugs, such as those used as part of a sex-change procedure or for hormone therapy for prostate cancer, your risk of breast cancer is increased.
  • Family history of breast cancer. If you have a close family member with breast cancer, you have a greater chance of developing the disease.
  • Klinefelter's syndrome. This genetic syndrome occurs when a boy is born with more than one copy of the X chromosome. Klinefelter's syndrome causes abnormal development of the testicles. As a result, men with this syndrome produce lower levels of certain male hormones (androgens) and more female hormones (estrogens).
  • Liver disease. Certain conditions, such as cirrhosis of the liver, can reduce male hormones and increase female hormones, increasing your risk of breast cancer.
  • Obesity. Fat cells convert androgens into estrogen. A higher number of fat cells in your body may result in increased estrogen and higher risk of breast cancer.
  • Radiation exposure. If you've received radiation treatments to your chest, such as those used to treat cancers in the chest, you're more likely to develop breast cancer later in life.
  • Testicle disease or surgery. Having inflamed testicles (orchitis) or surgery to remove a testicle (orchiectomy) can increase your risk of male breast cancer.
Start by seeing your family doctor or a general practitioner if you notice any unusual signs or symptoms that worry you. If your doctor thinks you may have breast cancer, you may be referred to a doctor who specializes in treating cancer (oncologist).

Because appointments can be brief, and because there's often a lot of ground to cover, it's a good idea to be well prepared. Here's some information to help you get ready and what to expect from your doctor.

What you can do?

  • Be aware of any pre-appointment restrictions, such as not eating solid food for a period of time before your appointment.
  • Write down your symptoms, including any that may seem unrelated to the reason why you scheduled the appointment.
  • Write down your key medical information, including other conditions.
  • Write down key personal information, including any recent life changes.
  • Make a list of all your medications, vitamins and supplements.
  • Ask a relative or friend to accompany you, to help you remember what the doctor says.
  • Write down questions to ask your doctor.
Your time with your doctor is limited, so preparing a list of questions can help you make the most of your time together. List your questions from most important to least important in case time runs out.

For male breast cancer, some basic questions to ask your doctor include:
  • What type of breast cancer do I have?
  • What is the stage of my cancer?
  • Has my cancer spread beyond the breast?
  • Can my cancer be cured?
  • Will I need more tests?
  • What are my treatment options?
  • What are the potential side effects of each option?
  • Is there a treatment option you feel is best for me?
  • How long will cancer treatment last?
  • How will cancer treatment affect my daily life?
  • I have these other health conditions. How can I best manage them together?
  • Should I see a specialist? What will that cost, and will my insurance cover it?
  • Are there any brochures or other printed material that I can take with me? What websites do you recommend?
In addition to the questions that you've prepared to ask your doctor, don't hesitate to ask questions that occur to you during your appointment.

What to expect from your doctor?

Your doctor is likely to ask you a number of questions. Being ready to answer them may make time to go over points you want to spend more time on. You may be asked:
  • What symptoms are you experiencing? How severe are they?
  • When did you first begin experiencing symptoms? Are they continuous or occasional?
  • Have any of your relatives been diagnosed with cancer? If so, what type of cancer and at what age were the family members diagnosed?

Diagnosing male breast cancer

Your doctor may conduct a number of diagnostic tests and procedures, such as:
  • Clinical breast exam. The doctor uses his or her fingertips to examine your breasts and surrounding areas for lumps or other changes. Your doctor assesses how large the lumps are, how they feel, and how close they are to your skin and muscles.
  • Imaging tests. Mammogram and ultrasound can detect suspicious masses in your breast tissue.
  • Biopsy. A fine needle is inserted into the breast to remove tissue for analysis in the laboratory. Test results can reveal whether you have breast cancer and if so, the type of breast cancer you have.

Determining the extent of the cancer

Determining the extent (stage) of your cancer helps your doctor evaluate treatment options. Biopsy, blood tests and imaging tests can be used to stage male breast cancer.

The stages of male breast cancer are:
  • Stage I. The tumor is no more than 2 centimeters (cm) in diameter (about 3/4 inch) and hasn't spread to the lymph nodes.
  • Stage II. The tumor may be up to 5 cm (about 2 inches) in diameter and may have spread to nearby lymph nodes. Or the tumor may be larger than 5 cm but no cancer cells are found in the lymph nodes.
  • Stage III. The tumor may be larger than 5 cm (about 2 inches) in diameter and may involve several nearby lymph nodes. Lymph nodes above the collarbone may also contain cancer cells.
  • Stage IV. Cancer at this stage has spread beyond the breast to distant areas, such as the bone, brain, liver or lungs.
To determine your male breast cancer treatment options, your doctor considers your cancer's stage, your overall health and your preferences. Male breast cancer treatment often involves surgery and may also include other treatments.

Surgery

The goal of surgery is to remove the tumor and surrounding breast tissue. The procedures include:
  • Removal of breast tissue and surrounding lymph nodes (modified radical mastectomy). The surgeon removes all of your breast tissue, including the nipple and areola, and some underarm lymph nodes.
  • Removal of one lymph node for testing (sentinel lymph node biopsy). The doctor identifies the lymph node most likely to be the first place your cancer cells would spread. That lymph node is removed and analyzed. If no cancer cells are found, there is a good chance that your breast cancer hasn't spread beyond your breast tissue.

Radiation therapy

Radiation therapy uses high-energy beams to kill cancer cells. In male breast cancer, radiation therapy may be used after surgery to eliminate any remaining cancer cells in the breast, chest muscles or armpit.

During radiation therapy, radiation comes from a large machine that moves around your body, directing the energy beams to precise points on your chest.

Chemotherapy

Chemotherapy uses medications to kill cancer cells. These medications may be administered through a vein in your arm (intravenously), in pill form or by both methods.

Your doctor might recommend chemotherapy after surgery to kill any cancer cells that might have spread outside your breast. Chemotherapy may also be an option for men with advanced breast cancer.

Hormone therapy

Most men with male breast cancer have tumors that rely on hormones to grow (hormone-sensitive). If your cancer is hormone-sensitive, your doctor may recommend hormone therapy.

Hormone therapy for male breast cancer often involves the medication tamoxifen, which is also used for women. Other hormone therapy medications used in women with breast cancer haven't been shown to be effective for men.
Receiving a cancer diagnosis can be shocking and upsetting. With time you'll find ways to cope with the stress and challenges of cancer and cancer treatment. Until then, you might find it helpful to consider:
  • Talking with someone. You may feel comfortable discussing your feelings with a friend or family member, or you might prefer meeting with a formal support group. Support groups for the families of cancer survivors also are available.
  • Prayer or meditation. You can pray or mediate on your own or receive guidance from a spiritual adviser or from an instructor.
  • Exercise. Gentle exercise may help boost your mood and make you feel better. Ask your doctor to recommend appropriate exercises.
  • Creative activities. Certain activities, such as art, dance and music, may help you feel less distressed. Some cancer centers have specially trained professionals who can guide you through these activities.
  • Relaxation exercises. Relaxation exercises help refocus your mind and help you relax. Relaxation exercises include guided imagery and progressive muscle relaxation. You can do relaxation exercises on your own, with an instructor or by listening to a recording that guides you through the exercises.

References

  1. Ruddy KJ, et al. Male breast cancer: Risk factors, biology, diagnosis, treatment and survivorship. Annals of Oncology. 2013;24:1343.
  2. Cameron JL, et al. Current Surgical Therapy. 11th ed. Philadelphia, Pa.: Elsevier Saunders; 2014. http://www.clinicalkey.com. Accessed Sept. 17, 2014.
  3. Gradishar WJ. Breast cancer in men. http://www.uptodate.com/home. Accessed Sept. 17, 2014.
  4. Chavez-Macgregor M, et al. Male breast cancer according to tumor subtype and race: A population-based study. Cancer. 2013;119:1611.
  5. Male breast cancer treatment (PDQ). National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/malebreast/patient. Accessed Nov. 19, 2014.
  6. Patten DK, et al. New approaches in the management of male breast cancer. Clinical Breast Cancer. 2013;13:309.
  7. Distress management. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed Sept. 17, 2014.
Feb. 17, 2015

Monday, October 2, 2017

“25 Breast Cancer Myths Busted!”




Know the difference between breast cancer facts and fiction? Here's the real deal on risks, symptoms, and more.

Myth: Only women with a family history of breast cancer are at risk:

Reality: Roughly 70% of women diagnosed with breast cancer have no identifiable risk factors for the disease. But the family-history risks are these: If a first-degree relative (a parent, sibling, or child) has had or has breast cancer, your risk of developing the disease approximately doubles. Having two first-degree relatives with the disease increases your risk even more.

Myth: Wearing an underwire bra increases your risk of getting breast cancer:

Reality: Claims that underwire bras compress the lymphatic system of the breast, causing toxins to accumulate and cause breast cancer, have been widely debunked as unscientific. The consensus is that neither the type of bra you wear nor the tightness of your underwear or other clothing has any connection to breast cancer risk.

Myth: Most breast lumps are cancerous:

Reality: Roughly 80% of lumps in women's breasts are caused by benign (noncancerous) changes, cysts, or other conditions. Doctors encourage women to report any changes at all, however, because catching breast cancer early is so beneficial. Your doctor may recommend a mammogram, ultrasound, or biopsy to determine whether a lump is cancerous.

Myth: Exposing a tumor to air during surgery causes cancer to spread:

Reality: Surgery doesn't cause breast cancer and it doesn't cause breast cancer to spread, as far as scientists can tell from the research so far. Your doctor may find out during surgery that your cancer is more widespread than previously thought, however. And some animal studies have shown that removing the primary tumor sometimes enables metastatic cancers to grow, but only temporarily; this has not been demonstrated in humans.

Myth: Breast implants can raise your cancer risk:

Reality: Women with breast implants are at no greater risk of getting breast cancer, according to research. Standard mammograms don't always work as well on these women, however, so additional X-rays are sometimes needed to more fully examine breast tissue.

Myth: All women have a 1-in-8 chance of getting breast cancer:

Reality: Your risk increases as you get older. A woman’s chance of being diagnosed with breast cancer is about 1 in 233 when she's in her 30s and rises to 1 in 8 by the time she’s reached 85.

Myth: Wearing antiperspirant increases your risk of getting breast cancer:

Reality: The American Cancer Society pooh-poohs this rumor, but admits that more research is needed. One small study did stumble on traces of parabens in a tiny sample of breast cancer tumors. Parabens, used as preservatives in some antiperspirants, have weak estrogen-like properties, but the study in question made no cause-and-effect connection between parabens and breast cancer, nor did it conclusively identify the source of the parabens found in tumors.

Myth: Small-breasted women have less chance of getting breast cancer:

Reality: There's no connection between the size of your breasts and your risk of getting breast cancer. Very large breasts may be harder to examine than small breasts, with clinical breast exams—and even mammograms and MRI's—more difficult to conduct. But all women, regardless of breast size, should commit to routine screenings and checkups.

Myth: Breast cancer always comes in the form of a lump:

Reality: A lump may indicate breast cancer (or one of many benign breast conditions), but women should also be on the alert for other kinds of changes that may be signs of cancer. These include swelling; skin irritation or dimpling; breast or nipple pain; nipple retraction (turning inward); redness, scaliness, or thickening of the nipple or breast skin; or a discharge other than breast milk. Breast cancer can also spread to underarm lymph nodes and cause swelling there before a tumor in the breast is large enough to be felt. On the other hand, a mammogram may pick up breast cancer that has no outward symptoms at all.

Myth: You can't get breast cancer after a mastectomy:

Reality: Some women do get breast cancer after a mastectomy, sometimes at the site of the scar. Or the original cancer may have spread. For women at high risk of breast cancer who have their breasts removed as a prophylactic or preventive measure, there's still a chance, though a small one, that they can get breast cancer. After prophylactic mastectomy a woman's risk for developing breast cancer is reduced by an average of 90%.

Myth: Your father's family history of breast cancer doesn't affect your risk as much as your mother's:

Reality: Your father's family history of breast cancer is just as important as your mother's in understanding your risk. But to find out about the risk stemming from your father's side of the family, you need to look primarily at the women; while men do get breast cancer, women are more vulnerable to it. Associated cancers in men (such as early-onset prostate or colon cancer) on either side are also important to factor in when doing a full family-tree risk assessment.

Myth: Caffeine causes breast cancer:

Reality: No causal connection has been found between drinking caffeine and getting breast cancer; in fact, some research suggests that caffeine may actually lower your risk. So far it's inconclusive whether breast soreness may be linked to caffeine.

Myth: If you're at risk for breast cancer, there's little you can do but watch for the signs:

Reality: There's a lot that women can do to lower their risk, including losing weight if they're obese, getting regular exercise, lowering or eliminating alcohol consumption, being rigorous about examining their own breasts, and having regular clinical exams and mammograms. Quitting smoking wouldn't hurt either. Some high-risk women also choose to have a prophylactic mastectomy to decrease their risk by roughly 90%. They can take other proactive steps such as having regular MRI's, exploring chemo-prevention with treatments such as tamoxifen, and participating in clinical trials.

Myth: Women with lumpy breasts (also known as fibrocystic breast changes) have a higher risk of developing breast cancer:

Reality: In the past, women with lumpy, dense, or fibrocystic breasts were believed to be at higher risk of getting breast cancer, but there doesn't appear to be a connection after all. However, when you have lumpy breasts, it can be trickier to differentiate normal tissue from cancerous tissue, so you may experience false alarms. Women with fibrocystic breasts often follow up their mammograms with an ultrasound.

Myth: Annual mammograms expose you to so much radiation that they increase your risk of cancer:

Reality: While it's true that radiation is used in mammography, the amount is so small that any associated risks are tiny when compared to the huge preventive benefits reaped from the test. Mammograms can detect lumps well before they can be felt or otherwise noticed, and the earlier that lumps are caught, the better one's chances for survival. The American Cancer Society recommends that women age 40 and older receive a screening mammogram every one to two years.

Myth: Needle biopsies can disturb cancer cells and cause them to spread to other parts of the body:

Reality: There's no conclusive evidence for this claim. Despite some previous concerns, a 2004 study found no increased spread of cancer among patients undergoing needle biopsies compared to those who did not have the procedure.

Myth: After heart disease, breast cancer is the nation's leading killer of women:

Reality: Breast cancer kills roughly 40,000 women a year in the United States but stroke (96,000 deaths), lung cancer (71,000), and chronic lower respiratory disease (67,000) are each responsible for more deaths annually.

Myth: If your mammography report is negative, there is nothing else to worry about:

Reality: Despite their importance for breast cancer screening and diagnosis, mammograms fail to detect around 10% to 20% of breast cancers. This is why clinical breast exams and, to some extent, breast self-exams are crucial pieces of the screening process.

Myth: Hair straighteners cause breast cancer in African-American women:

Reality: A large 2007 study funded by the National Cancer Institute found no increase in breast cancer risk due to the use of hair straighteners or relaxers. Study participants included African-American women who had used straighteners seven or more times a year for 20 years or longer.

Myth: Removing the entire breast gives you a better chance of surviving cancer than having a lumpectomy with radiation therapy:

Reality: Survival rates are about the same for women who have mastectomies and for women who choose the breast-conserving option of removing only part of the breast and following the surgery with radiation treatments. However, there are some cases—such as with extensive DCIS disease, the presence of BRCA gene mutations, or particularly large tumors—when lumpectomy and radiation may not be an appropriate treatment option.

Myth: Overweight women have the same breast cancer risk as other women:

Reality: Being overweight or obese does increase your breast cancer risk—especially if you're past menopause and/or you gained the weight later in life.

Myth: Fertility treatments increase the risk of getting breast cancer:

Reality: Given estrogen's connection to breast cancer, fertility treatments have come under suspicion. But several studies have found that prospective moms are likely to have no higher risk of breast cancer. As yet, no large, long-term, randomized studies have eliminated this concern entirely; it merits more research to find a definite answer.

Myth: Living near power lines can cause breast cancer:

Reality: A 2003 study aimed at explaining what appeared to be a high incidence of breast cancer in certain counties on Long Island, N.Y., found no link between the disease and electromagnetic fields emitted by power lines. An earlier study conducted in the Seattle area yielded a similar conclusion. Research into potential environmental risk factors is ongoing.

Myth: Having an abortion raises your risk of getting breast cancer:

Reality: Because abortion is believed to disrupt hormone cycles during pregnancy and breast cancer is linked to hormone levels, numerous studies have investigated a causal link—but found no conclusive evidence for one.

Myth: Breast cancer is preventable:

Reality: Alas, no. Although it is possible to identify risk factors (such as family history and inherited gene mutations) and make lifestyle changes that can lower your risk (reducing or eliminating alcohol consumption, losing weight, getting regular exercise and screenings, and quitting smoking), roughly 70% of women diagnosed with breast cancer have no identifiable risk factors, meaning that the disease occurs largely by chance and according to as-yet-unexplained factors.

Health Magazine (www.health.com)

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